Calnexin antibody (C-Term)
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- Target See all Calnexin (CANX) Antibodies
- Calnexin (CANX)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Orang-Utan
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Calnexin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Specificity
- Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.
- Cross-Reactivity (Details)
- Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.
- Purification
- Immunoaffinity chromatography
- Immunogen
- Synthetic peptide (KLH-coupled) from carboxyl terminal of human calnexin .
- Isotype
- IgG1
- Top Product
- Discover our top product CANX Primary Antibody
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- Application Notes
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther applications: user-optimized - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4, containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
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Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT?A receptor: characterization and subcellular distribution of sumoylated 5-HT?A receptors." in: Psychoneuroendocrinology, Vol. 38, Issue 11, pp. 2542-53, (2013) (PubMed).
: "Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation." in: Journal of bacteriology, Vol. 195, Issue 17, pp. 3914-24, (2013) (PubMed).
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Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT?A receptor: characterization and subcellular distribution of sumoylated 5-HT?A receptors." in: Psychoneuroendocrinology, Vol. 38, Issue 11, pp. 2542-53, (2013) (PubMed).
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- Target
- Calnexin (CANX)
- Alternative Name
- Calnexin (CANX Products)
- Synonyms
- CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
- Background
- Calnexin is calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may be involved in assisting protein assembly or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the ER quality control apparatus via the retention of incorrectly folded proteins.Calnexin Antibody, pAb, Rabbit is developed in rabbit hosts using a KLH-coupled synthetic peptide from carboxyl terminal of human calnexin protein (Swiss Prot: P27824).
- Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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