ZFAND5 antibody (AA 121-213) (AbBy Fluor® 350)
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- Target See all ZFAND5 Antibodies
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
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Binding Specificity
- AA 121-213
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZFAND5 antibody is conjugated to AbBy Fluor® 350
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZFAND5
- Isotype
- IgG
- Top Product
- Discover our top product ZFAND5 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
- Alternative Name
- ZFAND5 (ZFAND5 Products)
- Synonyms
- 2310057A04Rik antibody, 5830475F03Rik antibody, AA415485 antibody, Za20d2 antibody, Zfp216 antibody, ZA20D2 antibody, ZFAND5A antibody, ZNF216 antibody, wu:fi29f06 antibody, za20d2l antibody, zgc:56057 antibody, za20d2 antibody, zfand5 antibody, zfand5-a antibody, zfand5-b antibody, zfand5a antibody, znf216 antibody, id:ibd2892 antibody, wu:fb16d02 antibody, wu:fc67h07 antibody, zgc:73363 antibody, zinc finger, AN1-type domain 5 antibody, zinc finger AN1-type containing 5 antibody, zinc finger, AN1-type domain 5b antibody, zinc finger AN1-type containing 5 L homeolog antibody, zinc finger, AN1-type domain 5a antibody, Zfand5 antibody, ZFAND5 antibody, zfand5b antibody, zfand5.L antibody, zfand5a antibody
- Background
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Synonyms: ZA20D2, ZNF216, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5
Background: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
- Gene ID
- 7763
- UniProt
- O76080
- Pathways
- Platelet-derived growth Factor Receptor Signaling
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