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MAPKSP1 antibody (AA 5-100) (Alexa Fluor 555)

MAPKSP1 Reactivity: Mouse IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1696881
  • Target See all MAPKSP1 Antibodies
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Binding Specificity
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-100
    Reactivity
    • 26
    • 19
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 30
    • 3
    Rabbit
    Clonality
    • 30
    • 3
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPKSP1 antibody is conjugated to Alexa Fluor 555
    Application
    • 12
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Cow,Chicken,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MAP2K1IP1
    Isotype
    IgG
    Top Product
    Discover our top product MAPKSP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Alternative Name
    Map2k1ip1 (MAPKSP1 Products)
    Synonyms
    MAPKSP1 antibody, MAP2K1IP1 antibody, MAPBP antibody, MP1 antibody, PRO0633 antibody, Ragulator3 antibody, AW556229 antibody, Map2k1ip1 antibody, Mapbp antibody, Mapksp1 antibody, Mp1 antibody, mapksp1 antibody, zgc:110207 antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 antibody, LAMTOR3 antibody, Lamtor3 antibody, lamtor3 antibody
    Background

    Synonyms: LAMTOR3, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3, LTOR3_HUMAN, MAP2K1IP1, MEK binding partner 1, MEK partner 1, MEK-binding partner 1, Mitogen activated protein kinase kinase 1 interacting protein 1, Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein kinase scaffold protein 1, MP1, Ragulator complex protein LAMTOR3.

    Background: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]

    Pathways
    PI3K-Akt Signaling
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