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MAPKSP1 antibody (AA 1-124)

MAPKSP1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7167072
  • Target See all MAPKSP1 Antibodies
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Binding Specificity
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-124
    Reactivity
    • 27
    • 18
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    • 3
    Rabbit
    Clonality
    • 30
    • 3
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPKSP1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA)
    Isotype
    IgG
    Top Product
    Discover our top product MAPKSP1 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Alternative Name
    LAMTOR3 (MAPKSP1 Products)
    Synonyms
    MAPKSP1 antibody, MAP2K1IP1 antibody, MAPBP antibody, MP1 antibody, PRO0633 antibody, Ragulator3 antibody, AW556229 antibody, Map2k1ip1 antibody, Mapbp antibody, Mapksp1 antibody, Mp1 antibody, mapksp1 antibody, zgc:110207 antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 antibody, LAMTOR3 antibody, Lamtor3 antibody, lamtor3 antibody
    Background

    Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

    Aliases: LAMTOR3 antibody, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody, LTOR3_HUMAN antibody, MAP2K1IP1 antibody, MEK binding partner 1 antibody, MEK partner 1 antibody, MEK-binding partner 1 antibody, Mitogen activated protein kinase kinase 1 interacting protein 1 antibody, Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody, Mitogen-activated protein kinase scaffold protein 1 antibody, Mp1 antibody, Ragulator complex protein LAMTOR3 antibody

    UniProt
    Q9UHA4
    Pathways
    PI3K-Akt Signaling
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