LSD1 antibody (Alexa Fluor 647)

Catalog No. ABIN1698893

Product Details anti-LSD1 Antibody (Alexa Fluor 647)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSD1 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KDM1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: KDM1 (KDM1A Products)

Synonyms: AOF2 antibody, BHC110 antibody, KDM1 antibody, LSD1 antibody, 1810043O07Rik antibody, AA408884 antibody, Aof2 antibody, D4Ertd478e antibody, Kdm1 antibody, Lsd1 antibody, mKIAA0601 antibody, DKFZp459N2450 antibody, RGD1562975 antibody, aof2 antibody, kdm1 antibody, wu:fb82e06 antibody, wu:fc51a02 antibody, wu:fj36a05 antibody, wu:fj66b06 antibody, KDM1A antibody, lsd1 antibody, xLSD1 antibody, AtLSD1 antibody, F9F13.30 antibody, F9F13_30 antibody, LESION SIMULATING DISEASE antibody, LESION SIMULATING DISEASE 1 antibody, lysine demethylase 1A antibody, lysine (K)-specific demethylase 1A antibody, lysine (K)-specific demethylase 1a antibody, LSD1 zinc finger family protein antibody, KDM1A antibody, Kdm1a antibody, kdm1a antibody, LSD1 antibody

Background:

Synonyms: Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain protein 2, AOF 2, AOF2, BHC110, BRAF35 HDAC complex protein BHC110, BRAF35-HDAC complex protein BHC110, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin containing amine oxidase domain containing protein 2, Flavin-containing amine oxidase domain-containing protein 2, KDM 1, Kdm1a, KDM1A_HUMAN, KIAA0601, LSD 1, LSD1, Lysine K specic demethylase 1, Lysine K specic demethylase 1A, Lysine specic histone demethylase 1, Lysine specic histone demethylase 1A, Lysine-specic histone demethylase 1, Lysine-specic histone demethylase 1A.

Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect