TFAM antibody

Catalog No. ABIN1722377

Product Details anti-TFAM Antibody

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFAM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with human and rat mtTFA

Purification: Purified (protein G)

Immunogen: Human mtTFA [Swiss-Prot# Q00059]

Clone: 18G102B2E11

Isotype: IgG2b kappa

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/ IF(1:50) IHC - P(1:200) WB(1:1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris-glycine, NaCl 150 mM, ( pH 7.5), Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Alternative Name: Transcription factor A (TFAM Products)

Synonyms: tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody

Background: Mitochondrial transcription factor A (mtTFA) is one of the most important transcription factors related to mitochondrial genes. In turn, mtTFA regulates several pathways for metabolism and energy storage in cells. In several metabolic diseases, including insulin-resistance related diabetes, the activity of mtTFA is directly linked to interactions with oxidative stress and fat cell differentiation.

UniProt: Q00059

Pathways: Chromatin Binding