APC1 antibody (C-Term)

Catalog No. ABIN1731754

Product Details anti-APC1 Antibody

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with human ANAPC1

Purification: Antigen affinity purified

Immunogen: 17 amino acid peptide near the carboxy terminus of human APC1.

Isotype: IgG

Application Details

Application Notes:

Working dilution: ELISA, IHC - P (5 μg/mL), WB (1 - 2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Target Details for APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Alternative Name: ANAPC1 (ANAPC1 Products)

Synonyms: APC1 antibody, MCPR antibody, TSG24 antibody, DDBDRAFT_0186456 antibody, DDBDRAFT_0234263 antibody, DDB_0186456 antibody, DDB_0234263 antibody, 2610021O03Rik antibody, AI047775 antibody, AI853536 antibody, AW547281 antibody, Apc1 antibody, Mcpr antibody, tsg24 antibody, EMBRYO DEFECTIVE 2771 antibody, MOP10.10 antibody, MOP10_10 antibody, anaphase promoting complex subunit 1 antibody, E3 ubiquitin ligase antibody, ANAPC1 antibody, Anapc1 antibody, CC1G_09696 antibody, anapc1 antibody, EMB2771 antibody

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

UniProt: Q9H1A4