XPC antibody (C-Term)

Catalog No. ABIN375331

Product Details anti-XPC Antibody

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Reacts with human 105 kDa XPC protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross reacts with mouse protein due to sequence homology

Purification: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of human XPC protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for XPC

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Alternative Name: DNA Repair Protein Complementing XP-C Cells (XPC Products)

Synonyms: RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody

Background: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A.

UniProt: Q01831

Pathways: p53 Signaling, DNA Damage Repair