Kallikrein 11 antibody (AA 68-82)

Catalog No. ABIN1736153

Product Details anti-Kallikrein 11 Antibody

Target: Kallikrein 11 (KLK11)

Binding Specificity: AA 68-82

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 11 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Reacts with human Hippostasin/KLK11

Purification: Antigen affinity purified

Immunogen: Residues 68-82 [YIVHLGQHNLQKEEG] of the 35 kDa human hippostasin/KLK11protein. Sequence identity to mouse and rat: 86%.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/1 000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for Kallikrein 11

Target: Kallikrein 11 (KLK11)

Alternative Name: Kallikrein-11 (KLK11 Products)

Synonyms: KLK11 antibody, 2310015I08Rik antibody, Prss20 antibody, TLSP antibody, PRSS20 antibody, kallikrein related peptidase 11 antibody, kallikrein related-peptidase 11 antibody, kallikrein-related peptidase 11 antibody, KLK11 antibody, Klk11 antibody

Background: Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type.Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70 % of women with ovarian cancer and in 60 % of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

Pathways: Complement System