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QKI antibody (AA 1-341) (Biotin)

QKI Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal S147-6 Biotin
Catalog No. ABIN1741388
  • Target See all QKI Antibodies
    QKI (Protein Quaking (QKI))
    Binding Specificity
    • 21
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-341
    Reactivity
    • 53
    • 15
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 30
    • 25
    • 1
    Mouse
    Clonality
    • 31
    • 25
    Monoclonal
    Conjugate
    • 30
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This QKI antibody is conjugated to Biotin
    Application
    • 53
    • 40
    • 25
    • 21
    • 14
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Detects ~36-38 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.
    Clone
    S147-6
    Isotype
    IgG2b
    Top Product
    Discover our top product QKI Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN1741388 was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    QKI (Protein Quaking (QKI))
    Alternative Name
    QKI (QKI Products)
    Synonyms
    Hqk antibody, QK antibody, QK1 antibody, QK3 antibody, hqkI antibody, 1110003F05Rik antibody, 1500005P18 antibody, QkI antibody, l(17)-1Wis antibody, l17Wis1 antibody, Qki antibody, CQKI antibody, QKI-5 antibody, PqkI antibody, BqkI antibody, qk antibody, qk1 antibody, quaking antibody, Xqua antibody, qki antibody, EQKI antibody, EqkI antibody, QKI, KH domain containing RNA binding antibody, quaking antibody, QKI, KH domain containing, RNA binding S homeolog antibody, QKI, KH domain containing, RNA binding L homeolog antibody, QKI antibody, Qk antibody, qki.S antibody, qki.L antibody, Qki antibody
    Background
    QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.
    Gene ID
    9444
    UniProt
    Q96PU8
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