AGT antibody (AA 40-49)

Catalog No. ABIN180718

This Mouse Monoclonal antibody specifically detects AGT in EIA. It exhibits reactivity toward Human.

Quick Overview for AGT antibody (AA 40-49) (ABIN180718)

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGT antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: BGN-KA-4H

Product Details anti-AGT Antibody

Binding Specificity: AA 40-49

Characteristics: Synonyms: Angiotensin-1, Angiotensin-I, AGT-1, AGT1

Purification: Protein A chromatography

Immunogen: HMW conjugateSynthetic peptide corresponding to amino acids 40-49 of the angiotensinogen precursorconjugated to HMW carrier protein. AA Sequence: P-F-H-L-V-I-H-N-E-S(-C)

Isotype: IgG2a

Application Details

Application Notes: ELISADoes not react with angiotensin II, III or angiotensinogen in ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS buffer, pH 7.2, 0.1 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Alternative Name: Angiotensinogen

Background: Angiotensin-I is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.Synonyms: AGT-1, AGT1, Angiotensin-1, Angiotensin-I

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity