AGT antibody

Catalog No. ABIN180720

The Mouse Monoclonal anti-AGT antibody (Clone Ang II E7 (BGN-KA-4L)) (ABIN180720) specifically detects AGT in EIA. The antibody is reactive with Human, Rat, Horse, Sheep and Pig samples.

Quick Overview for AGT antibody (ABIN180720)

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Reactivity: Human, Rat, Horse, Sheep, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGT antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: Ang II E7 (BGN-KA-4L)

Product Details anti-AGT Antibody

Cross-Reactivity (Details): Species reactivity (expected):Rat, Sheep, Pig, Horse.
Species reactivity (tested):Human.

Characteristics: Synonyms: Angiotensin-2, Angiotensin-II, ANG2, ANG-2, ANG-II

Purification: Affinity Chromatography on Protein G

Immunogen: Peptide sequence corresponding to Angiotensin II, conjugated to a proprietary MolecularWeight Carrier. AA Sequence: DRVYIHPF

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Alternative Name: Angiotensinogen

Background: Angiotensin II is a vasopressor and stimulator of aldosterone secretion by the adrenal cortex, and functions also as a neurotransmitter. Angiotensin II is formed by catalytic action of the hydrolase called peptidyl dipeptidase A on C terminal oligopeptide (angiotensin I). In case of the cleavage of angiotensin I to the activated angiotensin II, it is called angiotensin converting enzyme (ACE), in case of the cleavage and inactivation of kinins, it is called kininase II (also called dipeptidyl carboxypeptidase I).Synonyms: ANG-2, ANG-II, ANG2, Angiotensin-2, Angiotensin-II

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity