CFP antibody

Catalog No. ABIN181118

Product Details anti-CFP Antibody

Target: CFP (Complement Factor P (CFP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CFP antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognises complement factor P, a 53 kDa glycosylated protein present in blood serum. This antibody does not inhibit function of complement factor P.

Characteristics: Synonyms: CFP, PFC, Complement factor P

Purification: Affinity chromatography on Protein A

Immunogen: Native purified factor P from human serum.

Clone: 01-10-24

Isotype: IgG1

Application Details

Application Notes: ELISA. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CFP

Target: CFP (Complement Factor P (CFP))

Alternative Name: Properdin (CFP Products)

Synonyms: BFD antibody, PFC antibody, PFD antibody, PROPERDIN antibody, BCFG antibody, Pfc antibody, Properdin antibody, complement factor properdin antibody, CFP antibody, Cfp antibody

Background: Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Synonyms: CFP, Complement factor P, PFC

Gene ID: 5199

UniProt: P27918

Pathways: Complement System