TREM1 antibody

Catalog No. ABIN1819858

Product Details anti-TREM1 Antibody

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TREM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Functional Studies (Func)

Specificity: Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.

Purification: Protein G purified

Immunogen: Mouse TREM-1 Fc fusion protein.
ImmunogenType: Fusion protein

Clone: L5-B8-2A12-3A12

Isotype: IgG2a

Application Details

Application Notes: Flo (1:25 - 1:100) IF, IHC-Fr

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for TREM1

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Alternative Name: TREM1 (TREM1 Products)

Synonyms: TREM1 antibody, CD354 antibody, TREM-1 antibody, triggering receptor expressed on myeloid cells 1 antibody, TREM1 antibody, Trem1 antibody, LOC100349504 antibody

Background: Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1

Gene ID: 54210