RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody

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Antigen
Synonyms MGC52995, rvb2, ecp51, tip48, cgi-46, reptin, tip49b, xReptin, MGC69398, RUVBL2, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B, wu:fi25f01, zreptin, mp47, p47
Alternatives
Epitope
N-Term
(17), (9), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(66), (17), (16), (11), (6), (2), (1), (1), (1)
Host
Rabbit
(46), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(57), (22), (19), (18), (15), (11), (4), (3), (3), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human RUVBL2
Sequence IDRPATGTGS KVGKLTLKTT EMETIYDLGT KMIESLTKDK VQAGDVITID
Predicted Reactivity Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name RUVBL2 (RUVBL2 Antibody Abstract)
Background RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities.
Molecular Weight 51 kDa
Gene ID 10856
NCBI Accession NP_006657, NM_006666
UniProt Q9Y230
Pathways Telomere Maintenance
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 463 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182549) WB Suggested Anti-RUVBL2 Antibody Titration: 0.2-1 ug/ml
Positive Contro...
Immunohistochemistry (IHC) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182549) anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182549) WB Suggested Anti-RUVBL2 Antibody
Positive Control: Lane 1:341 µg K562 lysate ...
Product cited in: Barthéléry, Jaishankar, Salli et al.: "Reptin52 expression during in vitro neural differentiation of human embryonic stem cells." in: Neuroscience letters, Vol. 452, Issue 1, pp. 47-51, 2009 (PubMed).

Background publications Bauer, Chauvet, Huber et al.: "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity." in: The EMBO journal, Vol. 19, Issue 22, pp. 6121-30, 2000 (PubMed).

Catalog No. ABIN182549
$289.00
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