Bromodomain Containing 2 (BRD2) (Middle Region) antibody

Details for Product No. ABIN182959
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Antigen
Synonyms D6S113E, FSH, FSRG1, NAT, RING3, RNF3, AW228947, D17H6S113E, Frg-1, Fsrg-1, Fsrg1, Nat, Ring3, Rnf3, mKIAA4005, brd2-a, fsh, fsrg1, nat, ring3, rnf3, brd2, fe47f02, fi85h05, wu:fe47f02, wu:fi85h05
Epitope
Middle Region
(8), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine), Xenopus laevis, Zebrafish (Danio rerio), Human, Chicken
(51), (15), (14), (13), (13), (13), (13)
Host
Rabbit
(41), (8), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(40), (12), (10), (9), (9), (6), (4), (4), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN182959
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human BRD2
Sequence QEQLRAVHEQ LAALSQGPIS KPKRKREKKE KKKKRKAEKH RGRAGADEDD
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, African clawed frog : 90 %, Zebrafish : 90 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against BRD2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name BRD2
Background BRD2 encodes a mitogen-activated kinase which localizes to the nucleus. BRD2 maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.
Molecular Weight 88 kDa
Gene ID 6046
NCBI Accession NP_005095, NM_005104
UniProt P25440
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Proteolysis / Ubiquitin
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 801 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Bromodomain Containing 2 (BRD2) (Middle Region) antibody WB Suggested Anti-BRD2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Background publications Pal, Evgrafov, Tabares et al.: "BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy." in: American journal of human genetics, Vol. 73, Issue 2, pp. 261-70, 2003 (PubMed).

Validation Images
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