STAT5B antibody (Middle Region)

Catalog No. ABIN183452

The Rabbit Polyclonal anti-STAT5B antibody is suitable to detect STAT5B in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Sheep and Goat. It has been validated for WB and IHC.

Quick Overview for STAT5B antibody (Middle Region) (ABIN183452)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STAT5B Antibody

Binding Specificity: Middle Region

Sequence: GTLSAHFRNM SLKRIKRSDR RGAESVTEEK FTILFDSQFS VGGNELVFQV

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 86%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against STAT5B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse STAT5B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 786 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5B

Background: Stat5 is a member of the STAT family. It mediates signaling of many cytokines and growth factors
Protein Interaction Partner: GHR, Jak2, INSR, Hoxb8, Stat5a, CENPJ, Epor,
Protein Size: 786

Molecular Weight: 86 kDa

Gene ID: 20851

NCBI Accession: NM_011489, NP_035619

UniProt: P42232

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation