Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2) (N-Term) antibody

Details for Product No. ABIN183621
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Antigen
Synonyms AU043397, G17, HOX12, PBX2MHC, PBX2P1, pbxy, wu:fb73g03
Epitope
N-Term
(8), (7), (6), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Human
(44), (17), (14), (14), (13), (13), (12), (1), (1)
Host
Rabbit
(31), (14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(32), (16), (10), (8), (4), (3), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN183621
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PBX2
Sequence PGGGRGGLGL VSGEPGGPGE PPGGGDPGGG SGGVPGGRGK QDIGDILQQI
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against PBX2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PBX2
Background PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Molecular Weight 46 kDa
Gene ID 5089
NCBI Accession NP_002577, NM_002586
UniProt P40425
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 430 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2) (N-Term) antibody WB Suggested Anti-PBX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
anti-Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2) (N-Term) antibody (2) WB Suggested Anti-PBX2
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500
Positive Control: HepG2 cell lysate
There is BioGPS gene expression data showing that PBX2 is expressed in HepG2
Background publications Lehner, Semple, Brown et al.: "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region." in: Genomics, Vol. 83, Issue 1, pp. 153-67, 2003 (PubMed).

Validation Images
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