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Details for Product No. ABIN184178

E2F Transcription Factor 1 (E2F1) (C-Term) antibody

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Antigen
Synonyms
RBP3, E2F-1, RBAP1, RBBP3, mKIAA4009, xE2F, CG6376, DRTF1/E2F, DmE2F-1, Dmel\\CG6376, Dp, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F, E2F1, E2f1, Evar(3)164, dE2F, dE2F1, dE2f, dE2f1, de2 ... show more
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN184178
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-E2F1 antibody: synthetic peptide directed towards the C terminal of human E2F1
Sequence REDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDC DFGDLTPLDF
Predicted Reactivity Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against E2F1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name E2F1
Background The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Molecular Weight 47kDa
Gene ID 1869
NCBI Accession NP_005216, NM_005225
UniProt Q01094
Research Area Cancer, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-E2F1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, 2004 (PubMed).

Alternatives for antigen "E2F Transcription Factor 1 (E2F1)", type "Antibodies"
Hosts (165), (61), (2), (1)
Reactivities (224), (87), (57), (25), (25), (25), (12), (1), (1), (1), (1), (1)
Applications (154), (73), (60), (51), (50), (27), (24), (10), (10), (7), (2), (2), (1), (1), (1)
Conjugates (10), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6)
Epitopes (29), (25), (17), (17), (10), (7), (7), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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