SNAP25 antibody

Catalog No. ABIN2017591

Product Details anti-SNAP25 Antibody

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAP25 antibody is un-conjugated

Application: Please inquire

Specificity: Rabbit Anti-SNAP25 Polyclonal Antibody detects endogenous levels of human, mouse, and rat SNAP25.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): This product has not been tested for other species yet.

Characteristics: Rabbit Anti-SNAP25 Polyclonal Antibody is developed in rabbit using Purified His-tagged human SNAP25 (Swiss Prot: Q5U0B5) full length recombinant protein.

Purification: Immunoaffinity chromatography

Immunogen: Purified His-tagged human SNAP25 full length recombinant protein.

Isotype: IgG

Application Details

Comment:

Positive Control: Hela, SH-SY5Y, mouse brain and rat brain.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Concentration: 0.5 mg/mL

Buffer: Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles.

Storage: 4 °C/-20 °C

Storage Comment: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.

Target Details for SNAP25

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Alternative Name: SNAP25 (SNAP25 Products)

Synonyms: RIC-4 antibody, RIC4 antibody, SEC9 antibody, SNAP antibody, SNAP-25 antibody, bA416N4.2 antibody, dJ1068F16.2 antibody, SNAP-25B antibody, SNAP-25a antibody, ric-4 antibody, ric4 antibody, sec9 antibody, snap-25 antibody, Bdr antibody, sp antibody, fj55h11 antibody, snap25 antibody, wu:fj55h11 antibody, Snap antibody, snap25.2 antibody, wu:fj33h05 antibody, synaptosome associated protein 25 antibody, synaptosome associated protein 25kDa S homeolog antibody, synaptosomal-associated protein, 25kDa antibody, synaptosomal-associated protein 25 antibody, synaptosome associated protein 25kDa antibody, synaptosome associated protein 25kDa L homeolog antibody, zgc:101731 antibody, synaptosomal-associated protein, 25b antibody, SNAP25 antibody, Snap25 antibody, snap25.S antibody, snap25 antibody, BACOIKO003_07 antibody, Tsp_10811 antibody, snap25.L antibody, zgc:101731 antibody, snap25b antibody

Background: SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that is involved in the molecular regulation of neurotransmitter release. It is part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. SNAP25 plays an important role toward achieving synaptic function of specific neuronal systems and it associates with proteins involved in vesicle docking and membrane fusion. In addition, SNAP25 plays an essential role in synaptic vesicle fusion and exocytosis.

UniProt: Q5U0B5

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport