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Details for Product No. ABIN184602

B-Cell Linker (BLNK) (C-Term) antibody

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Antigen
Synonyms Bca, BASH, Ly57, Ly-57, Lyw-57, SLP-65, AGM4, BLNK-S, LY57, SLP65, bca, BLNK, blnk, MGC147045
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN184602
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-KDSTRLKYAVKVS, from the C Terminus of the protein sequence according to NP_037446.1, NP_001107566.1.
Specificity This antibody is expected to recognize both reported isoforms (NP_037446.1, NP_001107566.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name BLNK / SLP-65
Background Synonyms: BLNK, SLP-65, B-cell linker, BASH, BLNK-s, Ly57, MGC111051, SLP65, B cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, OTTHUMP00000020167, Src homology 2 domain-containing leukocyte protein of 65 kDa, BLNK-S, LY57, OTTHUMP00000020168
Gene ID 29760, 17060
NCBI Accession NP_037446.1, NP_001107566.1
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 70 kDa band observed in lysates of cell line Daudi (calculated MW of 50.5 kDa according to NP_037446.1). The observed molecular weight corresponds to how SLP-65 is expected to run. However, when transiently expressed in HEK293, a 50 kDa band is observed. Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Fu, Turck, Kurosaki et al.: "BLNK: a central linker protein in B cell activation." in: Immunity, Vol. 9, Issue 1, pp. 93-103, 1998 (PubMed).

Alternatives for antigen "B-Cell Linker (BLNK)", type "Antibodies"
Hosts (98), (10), (9)
Reactivities (106), (73), (51), (15), (14), (14), (1)
Applications (80), (43), (40), (25), (17), (7), (6), (5), (4), (1), (1), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (18), (18), (12), (7), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
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