ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody

Details for Product No. ABIN184721
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Antigen
Synonyms TACE, adam17, si:dkey-81b15.2, adam18, cd156b, csvp, tace, CD156b, Tace, ADAM18, CD156B, CSVP, NISBD
Epitope
C-Term
(44), (22), (10), (7), (6), (5), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(168), (73), (70), (30), (30), (18), (1)
Host
Goat
(150), (11), (9), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(136), (80), (32), (24), (23), (20), (15), (13), (9), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN184721
374.27 $
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Immunogen Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3.
Specificity This antibody is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604).
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name ADAM17 / TACE
Background Synonyms: ADAM17, TACE, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), snake venom-like protease, ADAM metallopeptidase domain 17, ADAM18, CD156B, ADAM metallopeptidase domain 18, snake venom-like protease, tumor necrosis factor, alpha, converting enzyme
Gene ID 6868, 11491
NCBI Accession NP_003174
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 100 kDa band observed in human testis lysates (calculated MW of 93.0 kDa according to NP_003174.3). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody ABIN184721 staining (0.2µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
General Black, Rauch, Kozlosky et al.: "A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells." in: Nature, Vol. 385, Issue 6618, pp. 729-33, 1997 (PubMed).

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