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NLRP3 antibody (NLR Family, Pyrin Domain Containing 3) (C-Term)

Details for Product anti-NLRP3 Antibody No. ABIN184887, Supplier: Login to see New
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Synonyms CIAS1, Nalp3, avp, cias1, nalp3, pypaf1, agtavprl, AGTAVPRL, AII, AVP, C1orf7, CLR1.1, FCAS, FCU, MWS, NALP3, PYPAF1, AII/AVP, Cias1, Mmig1, Pypaf1
(38), (29), (17), (14), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
(164), (35), (29), (6), (5), (4), (2), (1), (1)
(86), (52), (30), (3)
This NLRP3 antibody is un-conjugated
(6), (6), (6), (5), (5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
ELISA, Western Blotting (WB)
(106), (86), (31), (27), (18), (13), (11), (8), (7), (4), (4), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Availability Available
Immunogen Peptide with sequence C-EKPELTVVFEPSW, from the C Terminus of the protein sequence according to NP_001073289.1, NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1.
Blocking Peptide Blocking peptide for this product available: ABIN369010
Specificity Variants (NP_001073289.1, NP_004886.3) encode the same isoform.
Cross-Reactivity Rat (Rattus), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CIAS1 / cryopyrin (NLRP3 Antibody Abstract)
Background Synonyms: NLRP3, CIAS1, FCU, MWS, FCAS, NALP3, C1orf7, PYPAF1, AII/AVP, AGTAVPRL, CRYOPYRIN, cold autoinflammatory syndrome 1, cryopyrin, Muckle-Wells syndrome, chromosome 1 open reading frame 7, PYRIN-containing APAF1-like protein 1, neuronal apoptosis inhibitor protein 3, angiotensin/vasopressin receptor AII/AVP-like, NLR family, pyrin domain containing 3, AII, AVP, CLR1.1, FLJ95925, AII/AVP receptor-like, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
Gene ID 114548
NCBI Accession NP_899632, NP_001073289, NP_004886, NP_001120934, NP_001120933
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: No signal obtained yet but low background observed in A431 lysates at up to 1 µg/mL. Flow cytometry: Customer finds it to work well in FC on human monocytes.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Hoffman, Mueller, Broide et al.: "Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome." in: Nature genetics, Vol. 29, Issue 3, pp. 301-5, 2001 (PubMed).

Catalog No. ABIN184887
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