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Details for Product No. ABIN185423

Spleen tyrosine Kinase (SYK) (Internal Region) antibody

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Antigen
Synonyms p72-Syk, Sykb, p72syk
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN185423
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-KYLQQNRHVKDKN, from the internal region of the protein sequence according to NP_003168.2, NP_001128524.1.
Specificity This antibody is expected to recognise both reported isoforms (NP_003168.2, NP_001128524.1). Reported pairs of variants represent identical proteins (NP_003168.2 and NP_001167638.1, NP_001128524.1 and NP_001167639.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Spleen tyrosine kinase / SYK
Background Synonyms: SYK, spleen tyrosine kinase, HGNC:11491, DKFZp313N1010, FLJ25043, FLJ37489, OTTHUMP00000021628, OTTHUMP00000021629
Gene ID 6850, 20963, 25155
NCBI Accession NP_003168.2, NP_001128524.1
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Approx 70 kDa band observed in Human Bone marrow, Lymph Node, and Spleen lysates (calculated MW of 72.1 kDa according to NP_003168.2). Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Rogers, Slack, Edwards et al.: "Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins." in: Immunity, Vol. 22, Issue 4, pp. 507-17, 2005 (PubMed).

Underhill, Rossnagle, Lowell et al.: "Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production." in: Blood, Vol. 106, Issue 7, pp. 2543-50, 2005 (PubMed).

Alternatives for antigen "Spleen tyrosine Kinase (SYK)", type "Antibodies"
Hosts (165), (59), (7)
Reactivities (226), (96), (88), (37), (27), (25), (12), (12)
Applications (171), (78), (74), (60), (59), (31), (30), (20), (3), (3), (2), (1), (1), (1), (1)
Conjugates (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (37), (26), (20), (11), (11), (7), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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