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Details for Product No. ABIN185533

Tryptophan Hydroxylase 2 (TPH2) (Internal Region) antibody

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Antigen
Synonyms ADHD7, NTPH, Ntph, tphR, wu:fq15a04, AU043594, tph2, tph1l, tphD2
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN185533
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-NKPNSGKNDDKGNK, from the internal region of the protein sequence according to NP_775489.2.
Cross-Reactivity Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Tryptophan hydroxylase 2 / TPH2
Background Synonyms: TPH2, tryptophan hydroxylase 2, HGNC:20692, FLJ37295, NTPH, neuronal tryptophan hydroxylase, ADHD7, MGC138871, MGC138872, tryptophan 5-monooxygenase 2
Gene ID 121278
NCBI Accession NP_775489.2
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Preliminary experiments in human brain lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
IHC: In paraffin embedded Human Brain Stem shows layered neuronal staining. Recommended concentration: 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Zhou, Roy, Lipsky et al.: "Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations." in: Archives of general psychiatry, Vol. 62, Issue 10, pp. 1109-18, 2005 (PubMed).

Alternatives for antigen "Tryptophan Hydroxylase 2 (TPH2)", type "Antibodies"
Hosts (46), (10), (1)
Reactivities (41), (32), (29), (18), (6), (5), (2), (1), (1), (1), (1)
Applications (41), (21), (10), (9), (4), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (8), (6), (2), (2), (2), (2), (1), (1), (1)
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