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Antibodies
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anti-P21-Activated Kinase 1 (PAK1) antibody
P21-Activated Kinase 1 (PAK1) antibody
| Antigen |
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| Synonyms |
PAKalpha, MGC130000, MGC130001, Paka, PAK-1, AW045634, PAK1, MGC83445, MGC139676 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (93), Rat (Rattus) (62), Mouse (Murine) (59), Dog (Canine) (18), Rabbit (17), Horse (Equine) (3), Pig (Porcine) (3), Chicken (2), Cow (Bovine) (2), Guinea Pig (1), Sheep (Ovine) (1)
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Application
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Immunofluorescence (IF) (56), Western Blotting (WB) (55), Flow Cytometry (FACS) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Immunohistochemistry (IHC) (18), ELISA (16), Enzyme Immunoassay (EIA) (14), Immunoprecipitation (IP) (10), Dot Blot (Dot) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1)
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| Catalog no. |
ABIN185685 |
| Quantity |
100 ug |
| Price |
501.80 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Alternative name
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PAK1
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Gene ID
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5058, 18479 (mouse), 29431 (rat)
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Immunogen
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C-NTEKQKKKPKMSDE
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Format
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Affinity-purified
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Description
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All names and symbols: PAK1, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) , MGC130000, MGC130001, PAKalpha , p21-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) . Official Symbol: PAK1. RefSeq number(s): NP_002567.3
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Specificity
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No cross-reactivity exptected with PAK3 Human, Mouse, Rat, Dog 545 aa
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Application Notes
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Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Approx 70kDa band observed in Human, Mouse and Rat Brain lysates (calculated MW of 60.6kDa according to NP_002567.3). Recommended concentration: 1-3µg/ml.
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Purification
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Buffer
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0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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Storage
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Aliquot and store at -20°C. Minimize freezing and thawing.
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Research Area
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Cancer, Apoptosis/Necrosis, Kinases/Phosphatases
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Restrictions
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For Research Use only
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Publications
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Zhao, Ma, Calon et al.: "Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease." in: Nature neuroscience, Vol. 9, Issue 2, pp. 234-42, 2006 (PubMed).
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Alternatives for antigen "P21-Activated Kinase 1 (PAK1)", type "Antibodies"
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Hosts
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Rabbit (88), Mouse (8), Goat (3)
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Reactivities
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Human (93), Rat (Rattus) (62), Mouse (Murine) (59), Dog (Canine) (18), Rabbit (17), Horse (Equine) (3), Pig (Porcine) (3), Chicken (2), Cow (Bovine) (2), Guinea Pig (1), Sheep (Ovine) (1)
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Applications
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Immunofluorescence (IF) (56), Western Blotting (WB) (55), Flow Cytometry (FACS) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Immunohistochemistry (IHC) (18), ELISA (16), Enzyme Immunoassay (EIA) (14), Immunoprecipitation (IP) (10), Dot Blot (Dot) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1)
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Conjugates
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Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
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Epitopes
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pThr212 (10), N-Term (3), pThr423 (2), T423 (1), pT212 (1), ppT423 (1)
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Alternatives 
