Cholinergic Receptor, Muscarinic 1 (CHRM1) (C-Term) antibody

Details for Product No. ABIN185701
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Antigen
Synonyms M1, CHRM1, HM1, M1R, mAChR, Chrm-1
Epitope
C-Term
(19), (12), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(63), (57), (39), (1)
Host
Goat
(70), (11)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (5), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(67), (40), (22), (10), (8), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Immunogen Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence according to NP_000729.2.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name M1 mAChR / CHRM1 (CHRM1 Antibody Abstract)
Background Synonyms: CHRM1, M1 mAChR, cholinergic receptor, muscarinic 1, HM1, M1, MGC30125, muscarinic acetylcholine receptor M1
Gene ID 1128, 12669, 25229
NCBI Accession NP_000729
Application Notes ELISA: antibody detection limit dilution 1:64000.
Western blot: Approx 50 kDa band observed in Mouse Heart and Rat Heart lysates (calculated MW of 51.4 kDa according to NP_000729.2). Recommended concentration: 0.3-1 µg/mL.
Restrictions For Research Use only
Format Liquid
Concentration 0.5mg/ml
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Cholinergic Receptor, Muscarinic 1 (CHRM1) (C-Term) antibody ABIN185701 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Pri...
anti-Cholinergic Receptor, Muscarinic 1 (CHRM1) (C-Term) antibody (2) ABIN185701 (0.3 µg/mL) staining of Mouse Heart lysate (35 µg protein in RIPA buffer)....
General Caccamo, Oddo, Billings et al.: "M1 receptors play a central role in modulating AD-like pathology in transgenic mice." in: Neuron, Vol. 49, Issue 5, pp. 671-82, 2006 (PubMed).

Validation Images
Catalog No. ABIN185701
325.97 $
Plus shipping costs $45.00
Quantity
Price
100 μg
325.97 $

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