ITGA2 antibody (AA 74-277)
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- Target See all ITGA2 Antibodies
- ITGA2 (Integrin alpha 2 (ITGA2))
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Binding Specificity
- AA 74-277
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGA2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Purpose
- Monoclonal Antibody to Integrin Alpha 2 (ITGa2)
- Sequence
- MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF- P SLIDVVVVCD ESNSIYPWDA VKNFLEKFVQ GLDIGPTKTQ VGLIQYANNP RVVFNLNTYK TKEEMIVATS QTSQYGGDLT NTFGAIQYAR KYAYSAASGG RRSATKVMVV VTDGESHDGS MLKAVIDQCN HDNILRFGIA VLGYLNRNAL DTKNLIKEIK AIASIPTERY FFNVSDEAAL LEKAGTLGEQ I
- Specificity
- The antibody is a mouse monoclonal antibody raised against ITGa2. It has been selected for its ability to recognize ITGa2 in immunohistochemical staining and western blotting.
- Purification
- Protein A + Protein G affinity chromatography
- Immunogen
- Recombinant Integrin Alpha 2 (ITGa2) corresdonding to Glu74~Val277 (Accession # P17301)
- Clone
- 1#
- Isotype
- IgG
- Top Product
- Discover our top product ITGA2 Primary Antibody
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- Application Notes
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Western blotting: 0.5-5 μg/mL Immunocytochemistry in formalin fixed cells: 5-30 μg/mL Immunohistochemistry in formalin fixed frozen section: 5-30 μg/mL Immunohistochemistry in paraffin section: 5-30 μg/mL Enzyme-linked Immunosorbent Assay: 0.05-2 μg/mL Optimal working dilutions must be determined by end user.
- Comment
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The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.
- Preservative
- ProClin
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid repeated freeze/thaw cycles
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- Expiry Date
- 24 months
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Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection." in: The Journal of biological chemistry, Vol. 291, Issue 28, pp. 14815-25, (2016) (PubMed).
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Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection." in: The Journal of biological chemistry, Vol. 291, Issue 28, pp. 14815-25, (2016) (PubMed).
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Alternative Name
- Integrin Alpha 2 (ITGA2 Products)
- Synonyms
- BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
- Background
- CD49b, BR, GPIa, VLA-2, VLAA2, Platelet membrane glycoprotein Ia, Alpha 2 Subunit Of VLA-2 Receptor, Very Late Activation Proteins 2 Receptor, Collagen receptor, VLA-2 alpha
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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