CTNNB1 antibody (N-Term)
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- Target See all CTNNB1 Antibodies
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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Binding Specificity
- AA 78-106, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CTNNB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- B, Zf, M, Rat, X
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the N-terminal region of human CTNNB1.
- Clone
- RB41157
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CTNNB1 Primary Antibody
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anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibody
KO Validated CTNNB1 Reactivity: Human WB, IHC, IF, FACS, IHC (p), IP, ICC, IHC (fro), ChIP, IHC (wm), CUT&RUN Host: Rabbit Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibodyCTNNB1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 692-721), (C-Term) antibodyCTNNB1 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB41124 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 2-781) antibodyCTNNB1 Reactivity: Human WB, IHC, ELISA, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 78-106), (N-Term) antibodyCTNNB1 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB41155 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 1-100) antibodyCTNNB1 Reactivity: Human, Mouse WB, IHC, ELISA, FACS, ICC, Neut Host: Mouse Monoclonal 7C5A2 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 632-781) antibodyCTNNB1 Reactivity: Human, Mouse, Rat, Monkey WB, IHC, ELISA, FACS Host: Mouse Monoclonal 5B6E9 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 682-781) antibodyCTNNB1 Reactivity: Human WB, ELISA, IF, PLA, RNAi Host: Mouse Monoclonal 1C9 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 Reactivity: Human WB, IHC, IF, FACS, StM Host: Rabbit Monoclonal CTNNB1-2030R unconjugated Recombinant Antibody
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 Reactivity: Human, Dog WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 1E10 unconjugated
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
- Alternative Name
- CTNNB1 (CTNNB1 Products)
- Synonyms
- Jup antibody, LOC100217813 antibody, CTNNB1 antibody, CTNNB antibody, Bfc antibody, Catnb antibody, Mesc antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, ctnnb1 antibody, CHBCAT antibody, MRD19 antibody, armadillo antibody, beta-catenin antibody, catenin beta 1 antibody, catenin (cadherin associated protein), beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 S homeolog antibody, catenin beta 1 L homeolog antibody, CTNNB1 antibody, Ctnnb1 antibody, ctnnb1 antibody, ctnnb1.S antibody, ctnnb1.L antibody
- Background
- Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2.
- Molecular Weight
- 85497
- NCBI Accession
- NP_001091679, NP_001091680, NP_001895
- UniProt
- P35222
- Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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