This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This VPS25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the C-terminal region of human VPS25.
VPS25 antibody, CG14750 antibody, Dmel\\CG14750 antibody, ESCRT-I antibody, ESCRT-II antibody, dVps25 antibody, l(2)44Db antibody, l(2)k08904 antibody, vps25 antibody, GB16268 antibody, derp9 antibody, eap20 antibody, fap20 antibody, DDBDRAFT_0189483 antibody, DDBDRAFT_0234026 antibody, DDB_0189483 antibody, DDB_0234026 antibody, 1110020N13Rik antibody, AW107467 antibody, D11Wsu68e antibody, im:6898134 antibody, zgc:162560 antibody, DERP9 antibody, EAP20 antibody, FAP20 antibody, vacuolar protein sorting 25 homolog antibody, vacuolar protein sorting 25 homolog (S. cerevisiae) pseudogene antibody, vacuolar protein sorting-associated protein 25 antibody, WNK lysine deficient protein kinase 4 antibody, Vacuolar protein sorting 25 antibody, vacuolar protein-sorting-associated protein 25 antibody, vacuolar protein sorting 25 homolog L homeolog antibody, vacuolar protein sorting 25 antibody, vacuolar protein sorting 25 homolog (S. cerevisiae) antibody, E2F/DP family winged-helix DNA-binding domain-containing protein antibody, VPS25 antibody, LOC459431 antibody, CpipJ_CPIJ010292 antibody, WNK4 antibody, Vps25 antibody, LOC412381 antibody, vps25.L antibody, vps25 antibody
Background
VPS25, VPS36 (MIM 610903), and SNF8 (MIM 610904) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS25, VPS36, and SNF8 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).