This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This XRCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XRCC2.
XRCC2
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Schwarz, Daley, Beckhaus, Dötsch, Bernhard: "Cell-free expression profiling of E. coli inner membrane proteins." in: Proteomics, Vol. 10, Issue 9, pp. 1762-79, (2010) (PubMed).
Briggs, Goldstein, McCauley, Zuvich, De Jager, Rioux, Ivinson, Compston, Hafler, Hauser, Oksenberg, Sawcer, Pericak-Vance, Haines, Barcellos: "Variation within DNA repair pathway genes and risk of multiple sclerosis." in: American journal of epidemiology, Vol. 172, Issue 2, pp. 217-24, (2010) (PubMed).
Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
Target
XRCC2
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC2))
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.