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MBD3 antibody

MBD3 Reactivity: Human WB Host: Mouse Monoclonal 995CT3-2-2 unconjugated
Catalog No. ABIN1882264
  • Target See all MBD3 Antibodies
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Reactivity
    • 70
    • 29
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 9
    • 2
    Mouse
    Clonality
    • 56
    • 14
    Monoclonal
    Conjugate
    • 42
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBD3 antibody is un-conjugated
    Application
    • 46
    • 29
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    Purified His-tagged MBD3 protein was used to produced this monoclonal antibody.
    Clone
    995CT3-2-2
    Isotype
    IgG1
    Top Product
    Discover our top product MBD3 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ee, McCannell, Tang, Fernandes, Hardy, Green, Chu, Fazzio: "An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5." in: Stem cell reports, Vol. 8, Issue 6, pp. 1488-1496, (2018) (PubMed).

    Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: "The DNA sequence and biology of human chromosome 19. ..." in: Nature, Vol. 428, Issue 6982, pp. 529-35, (2004) (PubMed).

    Tatematsu, Yamazaki, Ishikawa: "MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 8, pp. 677-88, (2000) (PubMed).

  • Target
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Alternative Name
    MBD3 (MBD3 Products)
    Background
    Does not bind DNA by itself. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing.
    Molecular Weight
    32844
    NCBI Accession
    NP_001268382, NP_001268383
    UniProt
    O95983
    Pathways
    Chromatin Binding
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