BIM antibody (AA 2-198)

Catalog No. ABIN1885509

Product Details anti-BIM Antibody

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Binding Specificity: AA 2-198

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Immunoaffinity chromotography purified IgG

Immunogen: Raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: -20 °C

Storage Comment: Can be stored at -20 °C, stable for one year.

Expiry Date: 12 months

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: Bim (BCL2L11 Products)

Synonyms: bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody

Background: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family.Bim is another BH3 domain containing protein which can induce apoptosis.Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w.The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Synonyms: Bim (1C2C8).Bcl-2 interacting protein, Bcl-2-related ovarian death gene, BOD, Bcl-2-like 11

NCBI Accession: NP_619527

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity