desert Hedgehog antibody (AA 135-388)

Catalog No. ABIN1886020

Product Details anti-desert Hedgehog Antibody

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Binding Specificity: AA 135-388

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This desert Hedgehog antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 388 of Dhh

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Alternative Name: Dhh (DHH Products)

Synonyms: GDXYM antibody, HHG-3 antibody, SRXY7 antibody, C78960 antibody, Xchh antibody, chh antibody, chh-a antibody, dhh antibody, dhh-1 antibody, dhh-A antibody, hh4 antibody, x-chh antibody, desert hedgehog antibody, desert hedgehog L homeolog antibody, desert hedgehog S homeolog antibody, DHH antibody, dhh antibody, Dhh antibody, dhh.L antibody, dhh.S antibody

Target Type: Species

Background: This gene encodes a member of the Hedgehog family.The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.This protein may be involved in both male gonadal differentiation and perineurial development.[provided by RefSeq]

Molecular Weight: 44 kDa

Gene ID: 50846

NCBI Accession: NM_021044, NP_066382

Pathways: Hedgehog Signaling