FEM1B antibody (AA 609-622)

Catalog No. ABIN1886892

Product Details anti-FEM1B Antibody

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Binding Specificity: AA 609-622

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 609 to 622 of human F1A alpha.This sequence is identical to the corresponding sequence of mouse FEM1b.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: F1A alpha (FEM1B Products)

Synonyms: F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody

Background: Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family.A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1beta.F1Aalpha/FEM1beta is the homologue of C.elegans sex determining protein FEM-1.FEM-1/F1Aalpha is cleaved by CED-3 and caspase.FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1.Overexpression of F1Aalpha induces apoptosis.F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis.F1Aalpha is expressed in a variety of human and mouse tissues.
Synonyms: F1A alpha

Molecular Weight: 70 kDa