FNIP2 antibody (C-Term)

Catalog No. ABIN1887136

Product Details anti-FNIP2 Antibody

Target: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human FNIP2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for FNIP2

Target: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Alternative Name: FNIP2 (FNIP2 Products)

Synonyms: LOC797213 antibody, FNIPL antibody, MAPO1 antibody, D630023B12Rik antibody, mKIAA1450 antibody, RGD1562174 antibody, folliculin interacting protein 2 antibody, si:ch211-42i9.8 antibody, FNIP2 antibody, si:ch211-42i9.8 antibody, fnip2 antibody, Fnip2 antibody

Background: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene.Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors.Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation.FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
Synonyms: Folliculin interacting protein 2, FNIPL

NCBI Accession: NP_065891