DRAXIN antibody (C-Term)

Catalog No. ABIN1887201

Product Details anti-DRAXIN Antibody

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAXIN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): At least three isoforms of Neucrin are known to exist, this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human Neucrin.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DRAXIN

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Alternative Name: NEUCRIN (DRAXIN Products)

Synonyms: C1orf187 antibody, draxin antibody, AGPA3119 antibody, UNQ3119 antibody, neucrin antibody, 2610109H07Rik antibody, MGC113312 antibody, dorsal inhibitory axon guidance protein antibody, DRAXIN antibody, Draxin antibody, draxin antibody

Background: Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures.It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin.Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures.Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.
Synonyms: Draxin, dorsal repulsive axon guidance protein