GRIK5 antibody (C-Term)

Catalog No. ABIN1887229

Product Details anti-GRIK5 Antibody

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): This Grik5 antibody does not cross-react with Grik4.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of the human Grik5.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for GRIK5

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Alternative Name: Grik5 (GRIK5 Products)

Synonyms: EAA2 antibody, GRIK2 antibody, GluK5 antibody, KA2 antibody, GRIK5 antibody, Glur6 antibody, ka2 antibody, eaa2 antibody, GluRgamma2 antibody, iGlu5 antibody, glutamate ionotropic receptor kainate type subunit 5 antibody, glutamate receptor, ionotropic, kainate 5 antibody, glutamate ionotropic receptor kainate type subunit 2 antibody, glutamate receptor, ionotropic, kainate 5 L homeolog antibody, glutamate receptor, ionotropic, kainate 5 (gamma 2) antibody, GRIK5 antibody, GRIK2 antibody, grik5 antibody, grik5.L antibody, Grik5 antibody

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels.Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1).Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2.In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
Synonyms: Grik5, Glutamate receptor ionotropic kainate 5, KA2, excitatory amino acid receptor 2, eea2

NCBI Accession: NP_002079

Pathways: Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis