ZNF281 antibody (C-Term)

Catalog No. ABIN1887292

Product Details anti-ZNF281 Antibody

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF281 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human ZFP281.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ZNF281

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Alternative Name: ZFP281 (ZNF281 Products)

Synonyms: ZNF281 antibody, zbp-99 antibody, znp-99 antibody, ZBP-99 antibody, ZNP-99 antibody, Znf281 antibody, zinc finger protein 281 antibody, ZNF281 antibody, znf281 antibody, Zfp281 antibody

Background: ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters.It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression.ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription.ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes.ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG.Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.
Synonyms: Zinc finger protein 281, ZNF281, ZBP-99, ZNP-99

Pathways: Embryonic Body Morphogenesis