LRFN1 antibody (C-Term)

Catalog No. ABIN1887349

Product Details anti-LRFN1 Antibody

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRFN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): This antibody is predicted to not cross-react with other members of the LRFN family.

Purification: Affinity chromatography purified via peptide column

Immunogen: LRFN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRFN1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for LRFN1

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Alternative Name: LRFN1 (LRFN1 Products)

Synonyms: SALM2 antibody, BC004018 antibody, Semo1 antibody, leucine rich repeat and fibronectin type III domain containing 1 antibody, LRFN1 antibody, Lrfn1 antibody

Background: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.At least two isoforms of LRFN1 are known to exist.
Synonyms: Leucine-rich repeat and fibronectin typeIII domain-containing protein 1, synaptic adhesion-like molecule 2

UniProt: Q9P244

Pathways: Synaptic Membrane