PLXDC1 antibody (Center)

Catalog No. ABIN1887608

Product Details anti-PLXDC1 Antibody

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLXDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the center of human TEM7.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for PLXDC1

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Alternative Name: TEM7 (PLXDC1 Products)

Synonyms: PLXDC1 antibody, TEM3 antibody, TEM7 antibody, 2410003I07Rik antibody, AI848450 antibody, Tem7 antibody, Arl12 antibody, plexin domain containing 1 antibody, PLXDC1 antibody, Plxdc1 antibody

Background: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues.Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors.At least four isoforms of TEM7 are known to exist, these include intracellular, secreted, and membrane-bound forms.A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa.High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.
Synonyms: Tumor endothelial marker 7, TEM3, plexin domain-containing protein 1, PLXDC1