SCUBE2 antibody (Center)

Catalog No. ABIN1887663

Product Details anti-SCUBE2 Antibody

Target: SCUBE2 (Signal Peptide, CUB Domain, EGF-Like 2 (SCUBE2))

Binding Specificity: Center

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCUBE2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human SCUBE2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SCUBE2

Target: SCUBE2 (Signal Peptide, CUB Domain, EGF-Like 2 (SCUBE2))

Alternative Name: SCUBE2 (SCUBE2 Products)

Synonyms: CEGB1 antibody, CEGF1 antibody, CEGP1 antibody, 4932442O19Rik antibody, Cegf1 antibody, Cegp1 antibody, RGD1563998 antibody, Scube2-ps1 antibody, wu:fc27f08 antibody, you antibody, signal peptide, CUB domain and EGF like domain containing 2 antibody, signal peptide, CUB domain, EGF-like 2 antibody, SCUBE2 antibody, Scube2 antibody, scube2 antibody

Background: SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium.SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1.SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
Synonyms: Signal peptide CUB domain EGF-like 2

NCBI Accession: NP_066025