TLR7 antibody (Middle Region)

Catalog No. ABIN1887811

Product Details anti-TLR7 Antibody

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Ion exchange chromatography purified

Immunogen: Peptide corresponding to 14 amino acids near the middle of mouse TLR7.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7 (TLR7 Products)

Synonyms: TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody

Background: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus.Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

NCBI Accession: NP_573474

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades