DCLK3 antibody (N-Term)

Catalog No. ABIN1887877

Product Details anti-DCLK3 Antibody

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLK3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the amino terminus of human DCLK3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DCLK3

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Alternative Name: DCLK3 (DCLK3 Products)

Synonyms: CLR antibody, DCAMKL3 antibody, DCDC3C antibody, DCK3 antibody, BC056929 antibody, C730036H08 antibody, Dcamkl3 antibody, RGD1309232 antibody, doublecortin like kinase 3 antibody, doublecortin-like kinase 3 antibody, DCLK3 antibody, Dclk3 antibody

Background: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family.DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development.The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly.In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.
Synonyms: Doublecortin kinase-like 3, DCK32, CLr, DCAMKL3, DCDC3C

NCBI Accession: NP_208382