MINA antibody (N-Term)

Catalog No. ABIN1887936

Product Details anti-MINA Antibody

Target: MINA (MYC Induced Nuclear Antigen (MINA))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MINA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human MINA.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for MINA

Target: MINA (MYC Induced Nuclear Antigen (MINA))

Alternative Name: MINA (MINA Products)

Synonyms: MDIG antibody, MINA53 antibody, NO52 antibody, ROX antibody, 1810047J07Rik antibody, 2410057H13Rik antibody, 3830408E23Rik antibody, AI449204 antibody, Mina53 antibody, mina antibody, MGC83527 antibody, MINA antibody, DKFZp459K0725 antibody, Mina antibody, ribosomal oxygenase 2 antibody, MYC induced nuclear antigen antibody, ribosomal oxygenase 2 L homeolog antibody, RIOX2 antibody, Riox2 antibody, MINA antibody, riox2.L antibody, riox2 antibody

Background: MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation.Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target.MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF.MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.
Synonyms: Myc induced nuclear antigen, MINA53, MDIG, NO52

NCBI Accession: NP_694822