Stathmin 1 antibody (N-Term)

Catalog No. ABIN1888033

Product Details anti-Stathmin 1 Antibody

Target: Stathmin 1 (STMN1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide from near the amino terminus of human op18.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: op18 (STMN1 Products)

Synonyms: C1orf215 antibody, LAP18 antibody, Lag antibody, OP18 antibody, PP17 antibody, PP19 antibody, PR22 antibody, SMN antibody, 19k antibody, Lap18 antibody, Op18 antibody, P18 antibody, P19 antibody, Pig antibody, Pp17 antibody, Pp18 antibody, Pp19 antibody, Pr22 antibody, Smn antibody, prosolin antibody, op18 antibody, stathmin antibody, stmn1 antibody, stmn1a antibody, lag antibody, lap18 antibody, pp17 antibody, pp19 antibody, pr22 antibody, smn antibody, fj43c10 antibody, wu:fj38b07 antibody, wu:fj43c10 antibody, zgc:110159 antibody, cb959 antibody, wu:fb14e04 antibody, zgc:136942 antibody, stmn1-a antibody, stmn1b antibody, xo35 antibody, stathmin 1 antibody, stathmin 1 S homeolog antibody, stathmin 1b antibody, stathmin 1a antibody, stathmin-like antibody, stathmin antibody, stathmin 1 L homeolog antibody, STMN1 antibody, Stmn1 antibody, stmn1.S antibody, stmn1 antibody, stmn1b antibody, stmn1a antibody, LOC100229194 antibody, stmn1.L antibody

Background: Op18 belongs to the stathmin family of genes and encodes a ubiquitous cytosolic phosphoprotein that may function as an intracellular relay integrating several signaling pathways such as those involved in cell proliferation and differentiation.Op18 has also been shown to be involved in the regulation of the microtubule filament system by destabilizing microtubules, thereby preventing assembly and promoting the disassembly of microtubules.More recently, op18 has been implicated as a potential target of the ASK1-p38 MAP kinase cascade, suggesting that the ASK1-p38 cascade may regulate microtubule dynamics through op18.Op18 is highly expressed in a wide variety of human malignancies, including leukemia, prostate cancer, ovarian carcinoma, and breast carcinoma, suggesting that op18 may be an ideal target for anti-cancer therapeutics.
Synonyms: oncoprotein 18, STMN1, Stathmin 1, Lag, LAP18

Pathways: MAPK Signaling, Microtubule Dynamics