ZNF219 antibody (N-Term)

Catalog No. ABIN1888235

Product Details anti-ZNF219 Antibody

Target: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF219 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.

Purification: Affinity chromatography purified via peptide column

Immunogen: ZFP219 antibody was raised against an 18 amino acid peptide near the amino terminus of human ZFP219.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ZNF219

Target: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Alternative Name: ZFP219 (ZNF219 Products)

Synonyms: ZNF219 antibody, ZFP219 antibody, Znf219 antibody, 2010302A17Rik antibody, zinc finger protein 219 antibody, ZNF219 antibody, Zfp219 antibody

Background: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor.Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis.ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus.Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
Synonyms: Zinc finger protein 219, ZNF219

NCBI Accession: NP_001095142