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MBP antibody

MBP Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal MBP101 unconjugated
Catalog No. ABIN3071582
  • Target See all MBP Antibodies
    MBP (Myelin Basic Protein (MBP))
    Reactivity
    • 107
    • 33
    • 31
    • 19
    • 11
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 78
    • 29
    • 9
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 80
    • 40
    Monoclonal
    Conjugate
    • 78
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBP antibody is un-conjugated
    Application
    • 78
    • 44
    • 42
    • 13
    • 13
    • 13
    • 11
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purpose
    Anti-Myelin Basic Protein Mouse Monoclonal Antibody
    Specificity
    This antibody reacts with residues 130-136 in human myelin basic protein (21.5 kDa and 18.5 kDa molecular forms). It also recognizes primate, rabbit, sheep, goat, rat, and mouse myelin basic protein.
    Cross-Reactivity
    Goat, Human, Mouse, Primate, Rabbit, Rat, Sheep
    Immunogen
    Purified human myelin basic protein.
    Clone
    MBP101
    Isotype
    IgG2b
    Top Product
    Discover our top product MBP Primary Antibody
  • Application Notes
    This antibody may be used in ELISA, immunohistochemistry, and Western blot procedures for detection and/or quantitation of myelin basic protein.ELISA: Human myelin basic protein coated on ELISA wells at 5 μg/mL, binding detected with HRP-conjugated goat anti-mouse IgG + ABTS substrate.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    Dilute in PBS or medium that is identical to that used in the assay system.
    Concentration
    Lot specific
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C,-80 °C
    Storage Comment
    This antibody is stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
  • Target
    MBP (Myelin Basic Protein (MBP))
    Alternative Name
    Myelin Basic Protein (MBP Products)
    Synonyms
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, MGC115135 antibody, myelin basic protein antibody, myelin basic protein a antibody, myelin basic protein L homeolog antibody, MBP antibody, Mbp antibody, mbpa antibody, mbp antibody, mbp.L antibody
    Background
    Myelin basic protein,The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. {PubMed:8544862}.,Myelin membrane, Peripheral membrane protein, Cytoplasmic side. Note=Cytoplasmic side of myelin., [Isoform 3]: Nucleus,MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein
    UniProt
    P02686
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