Add to Basket
Order hotline:
 |
+1 404 474 4654 |
 |
+1 888 205 9894 (TF) |
Protein-tyrosine Phosphatase 1C (PTPN6) (internal) antibody
| Antigen | Protein-tyrosine Phosphatase 1C (PTPN6) |
| Synonyms | HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1 |
| Epitope |
 Alternatives internal |
| Clonality | Polyclonal |
| Host |
Alternatives Goat |
| Reactivity |
Alternatives Human |
| Application |
Alternatives ELISA, Western Blotting (WB)
|
 |
1 reference available |
| Catalog no. | ABIN190820 |
| Quantity | 100 ug (Variants) |
| Price | 501.80 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | PTPN6 / SHP1 (internal) |
| Gene ID | 5777 |
| Immunogen | C-HTKNKREEKVKKQ |
| Format | Affinity-purified |
| Description | All names and symbols: PTPN6, SHP1 , protein tyrosine phosphatase, non-receptor type 6 , HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, 70 kda SHP-1L protein, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, protein-tyrosine phosphatase 1C. Official Symbol: PTPN6. RefSeq number(s): NP_536858.1, NP_002822.2 |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2) Human |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 70kDa band observed in lysates of cell lines Jurkat and U937 (calculated MW of 67.7kDa according to NP_536858.1 and 67.6kDa according to NP_002822.2). Recommended concentration: 0.2-0.5µg/ml. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Restrictions | For Research Use only |
Images
| ABIN190820 (0.2µg/ml) staining of Jurkat cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
Publications
| Publications |
Dubois, Bergeron, Kim et al.: "The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis." in: Nature medicine, Vol. 12, Issue 5, pp. 549-56, 2006 (PubMed).
|
Alternatives
Alternatives for antigen "Protein-tyrosine Phosphatase 1C (PTPN6)", type "Antibodies"
| Hosts | Rabbit (50), Mouse (23), Goat (9) |
| Reactivities | Human (76), Mouse (Murine) (34), Rat (Rattus) (34), Cow (Bovine) (15), Dog (Canine) (3), Pig (Porcine) (1) |
| Applications | Western Blotting (WB) (54), Immunofluorescence (IF) (35), Flow Cytometry (FACS) (19), Immunohistochemistry (IHC) (17), ELISA (13), Enzyme Immunoassay (EIA) (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunoprecipitation (IP) (9), Immunocytochemistry (ICC) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pTyr536 (5), internal (3), C-Term (2), Center (2) |
