PPAR-gamma (CRA-c) antibody

Antigen: PPAR-gamma (CRA-c)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN191899

Additional Information

Characteristics: Synonyms: PPARG, NR1C3, Peroxisome proliferator-activated receptor gamma

Swiss-Prot: P37231

Immunogen: Synthetic peptide surrounding amino acid 262 of human PPAR gamma isoform CRA-c

Cross-Reactivity: Human, Mouse (Murine)

Description: PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormonereceptor superfamily and functions as a transcriptional activator. PPAR gamma ispreferentially expressed in adipocyte as well as in vascular smooth muscle cells andmacrophage. Besides its role in mediating adipogenesis and lipids metabolism,PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. Theinhibition of PPAR gamma transcription activity is due to MAP kinase phosphorylation atserine 84 of PPARgamma.

Specificity: The antibody recognizes a ~33 kDa band, corresponding to PPARgamma isoform CRA-c). Species: Human, mouse. Others not tested. Pictures: Western blot analysis of PPARgamma in lysate from3T3 cells (Lane 1) and Jurkat Cells (Lane 2,3) usingantibody ABIN191899

Application Details

Application Notes: Western blotting (0.5-4 ug/ml). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.5 mg/ml

Purification: Aff - Purified

Buffer: PBS containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal

Restrictions: For Research Use only

Images

Western blot analysis of PPARgamma in lysate from 3T3 cells (Lane 1) and Jurkat Cells (Lane 2,3) using antibody ABIN191899